Stem Cell Applications in Parkinson’s Disease
نویسنده
چکیده
Parkinson’s disease (PD), characterized by the loss of dopaminergic neurons in the substantia nigra, is one of the most common neurodegenerative disorders in elderly people. However, few effective therapies are available for neurodegenerative diseases, including PD. Stem cell therapies have been studied as potentially effective treatment options for neurodegenerative diseases through mechanisms of neuronal regeneration and substitution. Stem cells can migrate into injured regions and produce new neurons and glia, as well as neuroprotective molecules to improve neuron survival in the region. The survival and integration of these transplanted stem cells is an important issue for the success of stem cell therapy in neurodegenerative disease. Recent research in animals shows the promise of stem cell transplantation as a powerful treatment for Parkinson’s disease, among other neurodegenerative diseases, in the near future. *Corresponding author: Yun Seob Song, Department of Urology, Soonchunhyang University School of Medicine, Seoul 140-743, Korea, Tel: +82-2-709-9114; E-mail: [email protected] Hong J Lee, Biomedical Research Institute, Chung-Ang University, College of Medicine, Seoul 156-756, Republic of Korea, Tel: +82-70-7555-2174; E-mail: [email protected] Received January 05, 2017; Accepted January 13, 2017; Published January 20, 2017 Citation: Choi SS, Ryu GH, Kim DH, Lee DS, Lee S, et al. (2017) Stem Cell Applications in Parkinson’s Disease. J Alzheimers Dis Parkinsonism 7: 300. doi: 10.4172/2161-0460.1000300 Copyright: © 2017 Choi SS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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